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Hiroaki Murata Selected Research

Acridine Orange

9/2018Long-term clinical outcome in patients with high-grade soft tissue sarcoma who were treated with surgical adjuvant therapy using acridine orange after intra-lesional or marginal resection.
1/2012Translational research of photodynamic therapy with acridine orange which targets cancer acidity.
9/2010Clinical outcomes of minimally invasive surgery using acridine orange for musculoskeletal sarcomas around the forearm, compared with conventional limb salvage surgery after wide resection.
1/2009A new therapeutic modality involving acridine orange excitation by photon energy used during reduction surgery for rhabdomyosarcomas.
5/2008A new limb salvage surgery in cases of high-grade soft tissue sarcoma using photodynamic surgery, followed by photo- and radiodynamic therapy with acridine orange.
11/2005Unfiltered xenon light is useful for photodynamic therapy with acridine orange.
5/2005Clinical outcome of a novel photodynamic therapy technique using acridine orange for synovial sarcomas.
3/2005Clinical trial of photodynamic therapy using acridine orange with/without low dose radiation as new limb salvage modality in musculoskeletal sarcomas.
1/2002Acridine orange excited by low-dose radiation has a strong cytocidal effect on mouse osteosarcoma.

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Hiroaki Murata Research Topics

Disease

30Neoplasms (Cancer)
09/2018 - 01/2002
14Osteosarcoma (Osteogenic Sarcoma)
02/2016 - 01/2002
8Sarcoma (Soft Tissue Sarcoma)
09/2018 - 03/2005
5Neoplasm Metastasis (Metastasis)
01/2018 - 03/2002
5Ulcer
05/2006 - 08/2002
3Type 2 Diabetes Mellitus (MODY)
03/2022 - 01/2022
3Pain (Aches)
03/2019 - 01/2008
3Bone Resorption
02/2013 - 07/2006
3Fibrosarcoma
02/2013 - 07/2010
3Margins of Excision
01/2011 - 11/2005
3Colonic Neoplasms (Colon Cancer)
08/2007 - 03/2002
3Stomach Ulcer (Gastric Ulcer)
05/2006 - 09/2003
2Obesity
03/2022 - 01/2022
2Hypotension (Low Blood Pressure)
01/2022 - 12/2021
2COVID-19
01/2022 - 10/2021
2Hemorrhage
09/2019 - 07/2009
2Venous Thrombosis (Deep-Vein Thrombosis)
09/2019 - 12/2018
2Intellectual Disability (Idiocy)
09/2019 - 12/2018
2Esophageal Achalasia (Megaesophagus)
08/2019 - 06/2014
2Aspiration Pneumonia
08/2019 - 06/2014
2Hyperalgesia
07/2019 - 08/2016
2Critical Illness (Critically Ill)
10/2018 - 10/2017
2Respiratory Insufficiency (Respiratory Failure)
01/2018 - 10/2017
2Surgical Wound
10/2012 - 03/2005
2Chondrosarcoma
10/2012 - 04/2008
2Necrosis
01/2011 - 01/2002
2Ewing Sarcoma (Sarcoma, Ewing)
01/2011 - 07/2008
2Carcinogenesis
02/2010 - 05/2006
2Infections
08/2009 - 10/2007
2Synovial Sarcoma (Synovioma)
06/2008 - 05/2005
2Colorectal Neoplasms (Colorectal Cancer)
08/2007 - 08/2004
2Peptic Ulcer (Peptic Ulcers)
05/2006 - 08/2002
2Breast Neoplasms (Breast Cancer)
06/2005 - 08/2002
2Carcinoma (Carcinomatosis)
10/2003 - 03/2002
1Encephalitis (Encephalitis, Rasmussen)
06/2022
1Thymoma (Thymic Carcinoma)
06/2022
1Myasthenia Gravis
06/2022
1Autoimmune Diseases of the Nervous System
06/2022
1Aortic Valve Stenosis (Aortic Stenosis)
12/2021
1Anaphylaxis (Anaphylactic Shock)
12/2021
1Bronchial Spasm
12/2021
1Syncope (Fainting)
11/2021
1Long QT Syndrome
11/2021

Drug/Important Bio-Agent (IBA)

9Acridine OrangeIBA
09/2018 - 01/2002
7Proteins (Proteins, Gene)FDA Link
07/2019 - 08/2002
61-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2012 - 03/2005
5EnzymesIBA
01/2022 - 11/2005
5Zoledronic Acid (Zometa)FDA Link
08/2017 - 02/2009
5Diphosphonates (Bisphosphonates)IBA
08/2017 - 07/2006
4Pharmaceutical PreparationsIBA
07/2019 - 09/2002
4Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
08/2007 - 03/2002
3Thallium-201IBA
03/2019 - 04/2008
3Anesthetics (Anesthetic Agents)IBA
11/2018 - 01/2009
3Antineoplastic Agents (Antineoplastics)IBA
01/2018 - 07/2010
3Oxygen (Dioxygen)IBA
10/2017 - 03/2007
3sulforaphaneIBA
03/2013 - 09/2006
3Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2007 - 03/2002
3Cimetidine (Biomet)FDA LinkGeneric
11/2005 - 08/2002
2Glucose (Dextrose)FDA LinkGeneric
03/2022 - 01/2022
2edoxabanIBA
09/2019 - 12/2018
2Warfarin (Coumadin)FDA LinkGeneric
09/2019 - 12/2018
2Carbon DioxideIBA
08/2019 - 06/2014
2Protons (Proton)IBA
01/2012 - 03/2007
2Fluorouracil (Carac)FDA LinkGeneric
07/2010 - 08/2007
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2009 - 08/2007
2Celecoxib (Celebrex)FDA Link
08/2007 - 10/2003
2Prostaglandins EIBA
11/2005 - 10/2003
2AcidsIBA
01/2005 - 08/2002
2ecabetIBA
09/2003 - 08/2002
1AutoantibodiesIBA
06/2022
1AntibodiesIBA
06/2022
1Cholinergic ReceptorsIBA
06/2022
1anti-titin autoantibodyIBA
06/2022
1ConnectinIBA
06/2022
1lipoprotein cholesterolIBA
01/2022
1HDL CholesterolIBA
01/2022
1Triglycerides (Triacylglycerol)IBA
01/2022
1SugammadexIBA
12/2021
1Epinephrine (Adrenaline)FDA LinkGeneric
12/2021
1Norepinephrine (Noradrenaline)FDA LinkGeneric
12/2021
1Glucagon (Glukagon)FDA Link
12/2021
1Propranolol (Inderal)FDA LinkGeneric
11/2021

Therapy/Procedure

16Therapeutics
09/2018 - 01/2002
10Drug Therapy (Chemotherapy)
07/2019 - 06/2005
6Photochemotherapy (Photodynamic Therapy)
12/2017 - 03/2005
5General Anesthesia
12/2021 - 07/2009
4Radiotherapy
01/2018 - 01/2002
4Limb Salvage
09/2010 - 03/2005
3Catheters
11/2021 - 04/2010
3Anesthesia
08/2019 - 07/2009
3Positive-Pressure Respiration (Positive End-Expiratory Pressure)
08/2019 - 06/2014
2Myotomy
08/2019 - 06/2014
2Renal Dialysis (Hemodialysis)
10/2018 - 05/2006
2Myocutaneous Flap
10/2012 - 01/2011
1Extracorporeal Membrane Oxygenation
01/2022
1Stents
01/2022
1Transcatheter Aortic Valve Replacement
12/2021
1Epidural Analgesia
11/2021
1Conduction Anesthesia (Regional Anesthesia)
10/2021
1Cardiopulmonary Bypass (Heart-Lung Bypass)
04/2021